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⇧ ⇧ Click above to watch Chromperfect 10 video ⇧ ⇧

Chromatography Data System, software for HPLC & GC 

Chromperfect Version 10 Has Arrived

Faster, Smarter, Built for Compliance

Chromperfect is the world’s longest-established independent chromatography data system (CDS), delivering reliable data acquisition, control, and compliance solutions for HPLC and GC systems. Proudly developed in the USA since 1982, we remain the only independent CDS provider in the country — trusted by labs worldwide for over four decades.

Why Labs Choose Chromperfect

Power. Simplicity. Compliance. Without the Complexity.

21 CFR Part 11 Compliance  

Complete audit trail, user role management, and electronic records security.

Instrument Compatibility

Integrates with leading HPLC & GC systems from Agilent, Shimadzu, Thermo, and more.

User-Friendly Interface

Logical workflows and multi-window layouts reduce training time and error risk.

Flexible Deployment

Scalable from standalone PCs to enterprise-level networks with remote access.​​

USA map showing Chromperfect's headquarters and service regions

The ONLY remaining Independent CDS developer in the USA

Pioneering Chromatography Innovation Since 1982

Chromperfect has proudly served the scientific community for over four decades. Founded in the USA in 1982, we are the only remaining independent chromatography data system (CDS) developer in the country. Our long-standing commitment to excellence has delivered robust, compliant, and user-friendly solutions to laboratories worldwide.

From introducing one of the first Windows-based CDS platforms to developing advanced tools for 21 CFR Part 11 compliance, Chromperfect has continually pushed the boundaries of performance and simplicity.

With Version 10, we continue to lead—offering powerful features designed for modern analytical workflows, while retaining the reliability and flexibility our users trust.

Screenshot showing Chromperfect compliance features and CFR 21 Part 11

Built for Compliance — CFR 21 Part 11 Ready

Chromperfect is fully compliant with FDA 21 CFR Part 11 regulations, ensuring your lab meets the highest standards for data integrity and audit readiness.

  • Secure, role-based user access

  • Full audit trail with time-stamped entries

  • Electronic signature support

  • Backup and recovery systems

Works with Your Lab's Instruments

Agilent Technologies logo – Agilent instruments work with Chromperfect
Thermo Fisher Scientific logo – Thermo Fisher GC/HPLC integration
PerkinElmer logo – PerkinElmer chromatography software compatibility
Shimadzu logo – Shimadzu GC/HPLC systems supported by Chromperfect
Scion Instruments logo – Works with Chromperfect chromatography software
Inficon logo – Inficon gas analysis instruments compatible with Chromperfect
Teledyne logo – Teledyne GC systems run with Chromperfect CDS
Agilent Technologies logo – Agilent instruments work with Chromperfect
Thermo Fisher Scientific logo – Thermo Fisher GC/HPLC integration
PerkinElmer logo – PerkinElmer chromatography software compatibility
Shimadzu logo – Shimadzu GC/HPLC systems supported by Chromperfect
Scion Instruments logo – Works with Chromperfect chromatography software
Inficon logo – Inficon gas analysis instruments compatible with Chromperfect
Teledyne logo – Teledyne GC systems run with Chromperfect CDS

Chromperfect integrates with industry-standard HPLC & GC systems — including Agilent, Shimadzu, Thermo Fisher, and more.

Chromperfect UI showing audit trail and data integrity features

Upgrade to Version 10 — Faster, Smarter, and Built for the Future

Chromperfect Version 10 represents the most advanced release in our 40+ year history. With faster performance, enhanced compliance features, and a refreshed user interface, upgrading is easy — and worth it.

Key Upgrade Benefits

  • New high-speed data engine

  • Optimized UI for faster workflows

  • Enhanced CFR 21 Part 11 compliance tools

  • Expanded instrument compatibility

  • Smooth transition from older versions (V6–V9)

Specialized Application Modules 

Chromperfect offers a suite of specialized modules designed to meet the unique analytical needs of various industries. Each module integrates seamlessly with the Chromperfect platform, providing tailored solutions for specific applications.

1. SEC / GPC Module

  • Purpose: Size Exclusion Chromatography (SEC) and Gel Permeation Chromatography (GPC) analysis.

  • Features: Produces calibrations and reports for analyzing large molecules such as proteins or polymers.

2. Natural Gas Reporter

  • Purpose: Characterization of natural gas and its condensates.

  • Features: Estimates heating values and Reid vapor pressure, providing critical data for the natural gas industry.

3. Interpret Cannabinoids

  • Purpose: Analysis of cannabinoid profiles.

  • Features: Tailored for cannabis laboratories to interpret complex cannabinoid data accurately.

4. PCB Reporter

  • Purpose: Characterization of Polychlorinated Biphenyl (PCB) mixtures.

  • Features: Integrates raw data with calibration files to produce comprehensive reports, capable of analyzing up to thirty different Aroclors.

5. Modbus Integration

  • Purpose: Communication with Programmable Logic Controllers (PLCs).

  • Features: Acts as a MODBUS slave device, storing data generated by Chromperfect modules and making it accessible to PLCs.

6. Process Control

  • Purpose: Automation and management of multi-stream production processes.

  • Features: Controls multiple instruments, manages sampling schedules, and integrates temperature control, alarms, and MODBUS output for comprehensive process automation.

7. CP Automation

  • Purpose: Streamline and automate repetitive chromatography tasks.

  • Features: Manages autosamplers, valves, detectors, and other instruments with precision. Supports custom automation scripts, scheduled sequences, and fail-safe operations to increase throughput and reduce manual intervention.

8. New Database Module

  • Purpose: Centralized data management for secure, scalable deployments.

  • Features: Modern SQL-based backend designed for CFR compliance and multi-user access. Enhances performance, traceability, and remote accessibility across laboratories, supporting both standalone and enterprise network environments.

Powerful Tools for Chromatography Labs

From data acquisition to compliance and automation, Chromperfect Version 10 delivers a full suite of tools for today’s analytical laboratories.

Lab technician presenting chromatography software training session

Real-Time Instrument Control


Acquire chromatographic data directly from supported HPLC and GC systems with high-speed drivers and precise timing.

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Flexible Data Handling

Perform peak integration, quantification, and calculations with advanced options for multi-level calibration and custom fields.

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Workflow Automation

Run scheduled batches, chain methods, and build conditional workflows using scripting tools and templates.

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Precision Reporting Built for Scientists

 

Create customized, publication-ready reports in PDF, Excel, and formats compatible with third-party systems.

Discover the Chromperfect Advantage

Software built for GC & HPLC professionals who demand performance, compliance, and reliability - without the complexity

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